D.DLab is a design-led technological research group positioning architectural design as a driving force in tackling one of the most significant global challenges of our time – the climate crisis in the context of the built environment. The architecture, engineering, and construction industries are responsible for 40% of global CO2 emissions, 30% of global waste production and 50% of raw resource consumption. Additionally, these sectors significantly impacts biodiversity directly affecting human health and well-being. In D.DLab we address these urgencies through three interconnected design-for-sustainability trajectories, aiming to generate new knowledge for architectural design.